"Discussion
... In this manuscript, we present a case of SPTCL [subcutaneous panniculitis-like T-cell lymphoma] that developed following the Ad26 viral vector–based COVID-19 vaccine (Janssen Pharmaceuticals). Although causation cannot be established in this single case, this case supports the understanding that certain immunologic triggers, such as a modified adenovirus vaccine, may contribute to the development or exacerbation of SPTCL. Aberrant immune function or lymphocyte hyperstimulation may also be responsible. For example, an association has been established between SPTCL and systemic lupus erythematosus, Sjögren’s syndrome, type 1 diabetes mellitus, and juvenile idiopathic arthritis."
© 2022 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc.
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